Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease Article

Jin, Mengmeng, Xu, Ranjie, Wang, Le et al. (2022). Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease . 29(7), 1135-+. 10.1016/j.stem.2022.06.007

Open Access

cited authors

  • Jin, Mengmeng; Xu, Ranjie; Wang, Le; Alam, Mahabub Maraj; Ma, Ziyuan; Zhu, Sining; Martini, Alessandra C; Jadali, Azadeh; Bernabucci, Matteo; Xie, Ping; Kwan, Kelvin Y; Pang, Zhiping P; Head, Elizabeth; Liu, Ying; Hart, Ronald P; Jiang, Peng

sustainable development goals

authors

publication date

  • July 7, 2022

keywords

  • ACTIVATION
  • BRAIN
  • CELLS
  • Cell & Tissue Engineering
  • Cell Biology
  • DYSTROPHIC MICROGLIA
  • HIPPOCAMPUS
  • INDIVIDUALS
  • Life Sciences & Biomedicine
  • MOUSE MODEL
  • PLASTICITY
  • PREVALENCE
  • Science & Technology
  • TAU PATHOLOGY

Digital Object Identifier (DOI)

publisher

  • CELL PRESS

start page

  • 1135

end page

  • +

volume

  • 29

issue

  • 7