Health effects and known pathology associated with the use of E-cigarettes Article

Esteban-Lopez, M, Perry, MD, Garbinski, LD et al. (2022). Health effects and known pathology associated with the use of E-cigarettes . 9 1357-1368. 10.1016/j.toxrep.2022.06.006

cited authors

  • Esteban-Lopez, M; Perry, MD; Garbinski, LD; Manevski, M; Andre, M; Ceyhan, Y; Caobi, A; Paul, P; Lau, LS; Ramelow, J; Owens, F; Souchak, J; Ales, E; El-Hage, N



  • In recent years, new nicotine delivery methods have emerged, and many users are choosing electronic cigarettes (e-cigarettes) over traditional tobacco cigarettes. E-cigarette use is very popular among adolescents, with more than 3.5 million currently using these products in the US. Despite the increased prevalence of e-cigarette use, there is limited knowledge regarding the health impact of e-cigarettes on the general population. Based on published findings by others, E-cigarette is associated with lung injury outbreak, which increased health and safety concerns related to consuming this product. Different components of e-cigarettes, including food-safe liquid solvents and flavorings, can cause health issues related to pneumonia, pulmonary injury, and bronchiolitis. In addition, e-cigarettes contain alarmingly high levels of carcinogens and toxicants that may have long-lasting effects on other organ systems, including the development of neurological manifestations, lung cancer, cardiovascular disorders, and tooth decay. Despite the well- documented potential for harm, e-cigarettes do not appear to increase susceptibility to SARS-CoV- 2 infection. Furthermore, some studies have found that e-cigarette users experience improvements in lung health and minimal adverse effects. Therefore, more studies are needed to provide a definitive conclusion on the long-term safety of e-cigarettes. The purpose of this review is to inform the readers about the possible health-risks associated with the use of e-cigarettes, especially among the group of young and young-adults, from a molecular biology point of view.

publication date

  • January 1, 2022

Digital Object Identifier (DOI)

start page

  • 1357

end page

  • 1368


  • 9