Metal-free regioselective formation of C-N and C-O bonds with the utilization of diaryliodonium salts in water: Facile synthesis of: N-Arylquinolones and aryloxyquinolines Article

Mehra, MK, Tantak, MP, Arun, V et al. (2017). Metal-free regioselective formation of C-N and C-O bonds with the utilization of diaryliodonium salts in water: Facile synthesis of: N-Arylquinolones and aryloxyquinolines . ORGANIC & BIOMOLECULAR CHEMISTRY, 15(23), 4956-4961. 10.1039/c7ob00940b

cited authors

  • Mehra, MK; Tantak, MP; Arun, V; Kumar, I; Kumar, D

authors

abstract

  • Regioselective construction of crucial C-N and C-O bonds leading to N-Arylquinolones and aryloxyquinolines has been accomplished by employing easily accessible diaryliodonium salts and quinolones in water under metal-and ligand-free conditions. This operationally simple strategy is significant due to mild reaction conditions, high product yields, recyclability of released iodoarenes and scalability to the gram level. The practical utility of the developed protocol was proved by the arylation of medicinally important heterocycles like acridin-9(10H)-one, 3-methylquinoxalin-2(1H)-one and 1H-benzo[d]imidazol-2(3H)-one.

publication date

  • January 1, 2017

published in

Digital Object Identifier (DOI)

start page

  • 4956

end page

  • 4961

volume

  • 15

issue

  • 23