Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation Article

Curreli, Francesca, Ahmed, Shahad, Victor, Sofia M Benedict et al. (2020). Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation . JOURNAL OF MEDICINAL CHEMISTRY, 63(4), 1724-1749. 10.1021/acs.jmedchem.9b02149

Open Access International Collaboration

cited authors

  • Curreli, Francesca; Ahmed, Shahad; Victor, Sofia M Benedict; Iusupov, Ildar R; Belov, Dmitry S; Markov, Pavel O; Kurkin, Alexander; Altieri, Andrea; Debnath, Asim K

sustainable development goals

authors

publication date

  • February 27, 2020

webpage

published in

keywords

  • Chemistry, Medicinal
  • EARLY SUBTYPE
  • ENV CLONES
  • ENVELOPE
  • HIV-1 ATTACHMENT INHIBITOR
  • IMMUNODEFICIENCY-VIRUS TYPE-1
  • INFECTIOUS MOLECULAR CLONES
  • Life Sciences & Biomedicine
  • NEUTRALIZATION
  • Pharmacology & Pharmacy
  • RECEPTOR
  • RESISTANCE
  • Science & Technology
  • X-RAY

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 1724

end page

  • 1749

volume

  • 63

issue

  • 4