Psychostimulant Rebound in Attention Deficit Disordered Boys Article

JOHNSTON, C, PELHAM, WE, HOZA, J et al. (1988). Psychostimulant Rebound in Attention Deficit Disordered Boys . JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 27(6), 806-810. 10.1097/00004583-198811000-00026

cited authors

  • JOHNSTON, C; PELHAM, WE; HOZA, J; STURGES, J

abstract

  • The evening behavior of 21 boys with attention deficit disorder was compared across days when they received either methylphenidate or placebo during the daytime. Parent ratings on one measure of evening behavior were significantly higher following two daytime administrations of 0.3 mg/kg methylphenidate rather than placebo. Individual data, however, showed large variability and few clinically significant rebound effects. No statistically significant rebound effects were found on a second measure nor were differences found between 0.3 mg/kg and 0.6 mg/kg doses administered twice daily. The data indicate that for the majority of children, behavioral rebound effects are neither large nor clinically significant. © 1988, The American Academy of Child and Adolescent Psychiatry. All rights reserved.

publication date

  • January 1, 1988

Digital Object Identifier (DOI)

start page

  • 806

end page

  • 810

volume

  • 27

issue

  • 6