Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy Article

Muralidharan, Priya, Acosta, Maria F, Gomez, Alexan I et al. (2021). Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy . 10(3), 10.3390/antiox10030427

Open Access

cited authors

  • Muralidharan, Priya; Acosta, Maria F; Gomez, Alexan I; Grijalva, Carissa; Tang, Haiyang; Yuan, Jason X-J; Mansour, Heidi M

sustainable development goals

publication date

  • March 1, 2021

keywords

  • Biochemistry & Molecular Biology
  • Chemistry, Medicinal
  • Food Science & Technology
  • Life Sciences & Biomedicine
  • Nrf2
  • Pharmacology & Pharmacy
  • ROCK inhibitor
  • Rho
  • Science & Technology
  • advanced spray drying
  • antioxidant
  • ligustrazine
  • lung vascular disease
  • monocrotaline (MCT)
  • rat model
  • respiratory drug delivery

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 10

issue

  • 3