Systematic analysis of purified astrocytes after SCI unveils Zeb2os function during astrogliosis Article

Wei, H, Wu, X, You, Y et al. (2021). Systematic analysis of purified astrocytes after SCI unveils Zeb2os function during astrogliosis . 34(5), 10.1016/j.celrep.2021.108721

cited authors

  • Wei, H; Wu, X; You, Y; Duran, RCD; Zheng, Y; Narayanan, KL; Hai, B; Li, X; Tallapragada, N; Prajapati, TJ; Kim, DH; Deneen, B; Cao, QL; Wu, JQ

authors

abstract

  • Wei et al. comprehensively investigate the coding and long non-coding gene expression changes and astrocyte-specific responses in injured spinal cord tissue and purified astrocytes from acute to chronic stages. Bioinformatic and functional analysis identify a conserved lncRNA Zeb2os that plays an essential role in reactive astrogliosis through the Zeb2os/Zeb2/Stat3 axis.

publication date

  • February 2, 2021

Digital Object Identifier (DOI)

volume

  • 34

issue

  • 5