Glycomic analysis of ovarian cancer: Past, present, and future Article

Abbott, KL. (2010). Glycomic analysis of ovarian cancer: Past, present, and future . Cancer Biomarkers, 8(4-5), 273-280. 10.3233/CBM-2011-0218

cited authors

  • Abbott, KL

abstract

  • Glycosylation is undeniably the most complex posttranslational modification. Glycan structures found on proteins and lipids are diverse, often changing in different tissues from normal physiologic conditions to diseases such as cancer. Glycomics encompasses the study of glycans along with the proteins and lipids to which they are attached. In this review we will discuss the glycomics of ovarian cancer from the pre- mass spectrometry era to current discoveries and finally to future potential clinical applications of research based on glycomic discoveries. © 2010/2011 - IOS Press and the authors. All rights reserved.

authors

publication date

  • December 1, 2010

published in

Digital Object Identifier (DOI)

start page

  • 273

end page

  • 280

volume

  • 8

issue

  • 4-5