The biennial Asian Conference on Transcription (ACT) covers a broad range of topics focused on the transcriptional regulatory networks of prokaryotes and eukaryotes. This year, the 15th ACT (www.asianconferencetranscription.com) was co-organised by the School of Biological Sciences, Universiti Sains Malaysia (USM), and the ACT committees in Jen Hotel, Penang, Malaysia from 31 July to 4 August 2017. There were 100 participants representing 13 countries. The Microbiology Society sponsored eight travel awards.