Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase Article

Winters, Maria, DuHadaway, James B, Pham, Khoa N et al. (2019). Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 162 455-464. 10.1016/j.ejmech.2018.11.010

Open Access

cited authors

  • Winters, Maria; DuHadaway, James B; Pham, Khoa N; Lewis-Ballester, Ariel; Badir, Shorouk; Wai, Jenny; Sheikh, Eesha; Yeh, Syun-Ru; Prendergast, George C; Muller, Alexander J; Malachowski, William P

sustainable development goals

authors

publication date

  • January 15, 2019

keywords

  • Antitumor therapy
  • B-CELLS
  • Chemistry, Medicinal
  • DISCOVERY
  • Diaryl oalkylhydroxylamines
  • Dual inhibitor
  • IDO1
  • IDO1 inhibition
  • IDO2 inhibition
  • IMMUNOTHERAPY
  • INSIGHTS
  • LUNG-CANCER
  • Life Sciences & Biomedicine
  • MECHANISM
  • Pan inhibition
  • Pharmacology & Pharmacy
  • SUBSTRATE
  • Science & Technology
  • TDO inhibition
  • TRYPTANTHRIN DERIVATIVES
  • TUMORAL IMMUNE RESISTANCE

Digital Object Identifier (DOI)

publisher

  • ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER

start page

  • 455

end page

  • 464

volume

  • 162