(+/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3 beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease Article

Ismaili, Lhassane, Monnin, Julie, Etievant, Adeline et al. (2021). (+/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3 beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease . ACS CHEMICAL NEUROSCIENCE, 12(8), 1328-1342. 10.1021/acschemneuro.0c00803

International Collaboration

cited authors

  • Ismaili, Lhassane; Monnin, Julie; Etievant, Adeline; Arribas, Raquel L; Viejo, Lucia; Refouvelet, Bernard; Soukup, Ondrej; Janockova, Jana; Hepnarova, Vendula; Korabecny, Jan; Kucera, Tomas; Jun, Daniel; Andrys, Rudolf; Musilek, Kamil; Baguet, Aurelie; Garcia-Frutos, Eva M; De Simone, Angela; Andrisano, Vincenza; Bartolini, Manuela; de Los Rios, Cristobal; Marco-Contelles, Jose; Haffen, Emmanuel

sustainable development goals

authors

publication date

  • April 2, 2021

webpage

published in

keywords

  • ACETYLCHOLINESTERASE INHIBITORS
  • AGGREGATION
  • ASSAY INTERFERENCE COMPOUNDS
  • Alzheimer's disease
  • Biginelli reaction
  • Biochemistry & Molecular Biology
  • COMPOUNDS PAINS
  • Chemistry, Medicinal
  • DRUG DISCOVERY
  • FLUORESCEIN
  • GSK 3 beta
  • HYBRIDS
  • Life Sciences & Biomedicine
  • MAO
  • Neurosciences
  • Neurosciences & Neurology
  • OXIDATIVE STRESS
  • PEPTIDE
  • Pharmacology & Pharmacy
  • Science & Technology
  • TARGET
  • calcium channel
  • cholinesterases

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 1328

end page

  • 1342

volume

  • 12

issue

  • 8