Selection by site-directed antibodies of small regions of peptides which are ordered in water.
Book Chapter
Dyson, HJ, Cross, KJ, Ostresh, J et al. (1986). Selection by site-directed antibodies of small regions of peptides which are ordered in water.
. 119 58-75.
Dyson, HJ, Cross, KJ, Ostresh, J et al. (1986). Selection by site-directed antibodies of small regions of peptides which are ordered in water.
. 119 58-75.
High resolution nuclear magnetic resonance has been used to study a short peptide which corresponds to the antigenic region of a larger peptide immunogen. This work shows that there is a strong conformational preference for a Type II beta-turn in solution. This observation has implications for the nature of the immunogenicity and antigenicity of peptide antigens as well as for the more general question of protein-folding mechanisms.
