Solid-phase synthesis of bis-cyclic guanidines from tripeptides Article

Acharya, AN, Ostresh, JM, Houghten, RA. (2001). Solid-phase synthesis of bis-cyclic guanidines from tripeptides . TETRAHEDRON, 57(50), 9911-9914. 10.1016/S0040-4020(01)01010-9

cited authors

  • Acharya, AN; Ostresh, JM; Houghten, RA

authors

abstract

  • An efficient method for the solid-phase synthesis of bis-cyclic guanidines from reduced tripeptides is described. The exhaustive reduction of the tripeptides generated tetra-amines that on treatment with cyanogen bromide, afforded bis-cyclic guanidines having three separate variable positions. © 2001 Elsevier Science Ltd. All rights reserved.

publication date

  • December 10, 2001

published in

Digital Object Identifier (DOI)

start page

  • 9911

end page

  • 9914

volume

  • 57

issue

  • 50