Immunological properties of purified Klebsiella pneumoniae heat-stable enterotoxin Article

Klipstein, FA, Engert, RF, Houghten, RA. (1983). Immunological properties of purified Klebsiella pneumoniae heat-stable enterotoxin . INFECTION AND IMMUNITY, 42(2), 838-841. 10.1128/iai.42.2.838-841.1983

cited authors

  • Klipstein, FA; Engert, RF; Houghten, RA

abstract

  • Klebsiella pneumoniae heat-stable enterotoxin was purified to apparent homogenicity by the same techniques used to purify Escherichia coli heat-stable enterotoxin. The two toxins had the same potency in the suckling mouse assay and showed immunological cross-reactivity in enzyme-linked immunosorbent assay, neutralization of secretory activity by specific hyperimmune antisera, and protection against active challenge in rats immunized with a vaccine containing synthetically produced E. coli heat-stable enterotoxin.

publication date

  • January 1, 1983

published in

Digital Object Identifier (DOI)

start page

  • 838

end page

  • 841

volume

  • 42

issue

  • 2