Biomimetic modeling of the decomposition of 2'-chloro-2'-deoxynucleotides by ribonucleotide reductases to give 3(2H)-furanones which can effect mechanism-based inactivation by Michael-type alkylation Article

Robins, MJ, Guo, ZQ, Samano, MC et al. (1996). Biomimetic modeling of the decomposition of 2'-chloro-2'-deoxynucleotides by ribonucleotide reductases to give 3(2H)-furanones which can effect mechanism-based inactivation by Michael-type alkylation . JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118(45), 11317-11318. 10.1021/ja962118e

cited authors

  • Robins, MJ; Guo, ZQ; Samano, MC; Wnuk, SF

sustainable development goals

authors

publication date

  • November 13, 1996

keywords

  • 2'-AZIDO-2'-DEOXYURIDINE 5'-DIPHOSPHATE
  • ACID RELATED-COMPOUNDS
  • CONVENIENT
  • Chemistry
  • Chemistry, Multidisciplinary
  • DIPHOSPHATE REDUCTASE
  • ESCHERICHIA-COLI
  • GENERATION
  • NUCLEOSIDES
  • OXIDATION
  • PROTEIN
  • Physical Sciences
  • SECONDARY ALCOHOLS
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 11317

end page

  • 11318

volume

  • 118

issue

  • 45