FIU Discovery

Identification of α1,2-fucosylated signaling and adhesion molecules in head and neck squamous cell carcinoma.  GLYCOBIOLOGY.  32:441-455.

Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.  115:E11033-E11042.

The extended cytoplasmic tail of the human B4GALNT2 is critical for its Golgi targeting and post-Golgi sorting.  FEBS JOURNAL.  285:3442-3463.

Cross regulation between mTOR signaling and O-GlcNAcylation

TNF differentially regulates ganglioside biosynthesis and expression in breast cancer cell lines.  PLOS ONE.  13.

Recombinant fungal lectin as a new tool to investigate O-GlcNAcylation processes.  GLYCOBIOLOGY.  27:123-128.

TNF up-regulates ST3GAL4 and sialyl-Lewis^x expression in lung epithelial cells through an intronic ATF2-responsive element.  BIOCHEMICAL JOURNAL.  474:65-78.

Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.  478:942-948.

Silencing the Nucleocytoplasmic O-GIcNAc Transferase Reduces Proliferation, Adhesion, and Migration of Cancer and Fetal Human Colon Cell Lines.  FRONTIERS IN ENDOCRINOLOGY.  7.

Over-sulfated glycosaminoglycans are alternative selectin ligands: insights into molecular interactions and possible role in breast cancer metastasis.  CLINICAL & EXPERIMENTAL METASTASIS.  30:919-931.

-L-Fucosidase Inhibition by Pyrrolidine-Ferrocene Hybrids: Rationalization of Ligand-Binding Properties by Structural Studies.  CHEMISTRY-A EUROPEAN JOURNAL.  19:9526-9533.

Estradiol Represses the G_D3 Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter.  PLOS ONE.  8.

TNF regulates sialyl-Lewis(x) and 6-sulfo-sialyl-Lewis(x) expression in human lung through up-regulation of ST3GAL4 transcript isoform BX.  BIOCHIMIE.  94:2045-2053.

Accumulation of Unusual Gangliosides G_Q3 and G_P3 in Breast Cancer Cells Expressing the G_D3 Synthase.  MOLECULES.  17:9559-9572.

The ganglioside G_D2 induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G_D3 synthase.  GLYCOBIOLOGY.  22:806-816.

Expression of G(D3) synthase modifies ganglioside profile and increases migration of MCF-7 breast cancer cells

Iminosugar-ferrocene conjugates as potential anticancer agents.  ORGANIC & BIOMOLECULAR CHEMISTRY.  10:5592-5597.

Role of Complex Gangliosides in Cancer Progression

Chapter 1.  1-20.

Identification of alpha 1,2-Fucosylated glycoproteins in head and neck squamous cell carcinoma.  GLYCOBIOLOGY. 1686-1686.

Control of cell signaling by O-GlcNAcylation, the sweet counterpart of phosphorylation.  1643-1643.

O-GlcNAc: Regulator of Signaling and Epigenetics Linked to X-linked Intellectual Disability

Detection and identification of O-GlcNAcylated proteins by proteomic approaches.  PROTEOMICS. 1039-1050.

How do gangliosides regulate RTKs signaling?.  751-767.