Kos, Lidia

Edit Your Profile

Kos, Lidia

Positions

Professor, University Graduate School , Office of Research and Economic Development

placeholder image

selected scholarly works & creative activities

Article
- 2021
  
  Pigmentation Affects Elastic Fiber Patterning and Biomechanical Behavior of the Murine Aortic Valve. FRONTIERS IN CARDIOVASCULAR MEDICINE. 8.
  Full Text via DOI: 10.3389/fcvm.2021.754560 Web of Science: 000743549800001
- 2021
  
  The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment. PIGMENT CELL & MELANOMA RESEARCH. 34:1084-1093.
  Full Text via DOI: 10.1111/pcmr.13002 Web of Science: 000679122600001
- 2021
  
  Abstract 2916: Characterization of a mouse model of leptomeningeal melanocytic disease. CANCER RESEARCH. 81:2916-2916.
  Full Text via DOI: 10.1158/1538-7445.am2021-2916
- 2021
  
  Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets. FRONTIERS IN CARDIOVASCULAR MEDICINE. 8.
  Full Text via DOI: 10.3389/fcvm.2021.678401 Web of Science: 000669668000001
- 2020
  
  Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays. SCIENTIFIC REPORTS. 10.
  Full Text via DOI: 10.1038/s41598-020-75890-0 Web of Science: 000589618700022
- 2020
  
  Simultaneous mapping of nanoscale topography and surface potential of charged surfaces by scanning ion conductance microscopy. NANOSCALE. 12:20737-20748.
  Full Text via DOI: 10.1039/d0nr04555a Web of Science: 000581650100016
- 2020
  
  Abstract 3956: Dystroglycan receptor and FER maintain melanoma dormancy in the vascular niche. CANCER RESEARCH. 80:3956-3956.
  Full Text via DOI: 10.1158/1538-7445.am2020-3956
- 2020
  
  Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. CELL REPORTS. 31.
  Full Text via DOI: 10.1016/j.celrep.2020.107765 Web of Science: 000541973800008
- 2015
  
  The transcription factors Ets1 and Sox10 interact during murine melanocyte development. DEVELOPMENTAL BIOLOGY. 407:300-312.
  Full Text via DOI: 10.1016/j.ydbio.2015.04.012 Web of Science: 000366068100011
- 2015
  
  Relationships between melanocytes, mechanical properties and extracellular matrix composition in mouse heart valves
  Full Text via DOI: 10.1615/JLongTermEffMedImplants.2015011748
- 2013
  
  Periodontal Ligament Cells Cultured Under Steady-Flow Environments Demonstrate Potential for Use in Heart Valve Tissue Engineering. TISSUE ENGINEERING PART A. 19:458-466.
  Full Text via DOI: 10.1089/ten.tea.2012.0149 Web of Science: 000313423700014
- 2012
  
  Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats. SCIENCE. 337:1536-1541.
  Full Text via DOI: 10.1126/science.1220893 Web of Science: 000308912900051
- 2011
  
  Quantification of carbon nanotube induced adhesion of osteoblast on hydroxyapatite using nano-scratch technique. NANOTECHNOLOGY. 22.
  Full Text via DOI: 10.1088/0957-4484/22/35/355703 Web of Science: 000294716900011
- 2011
  
  Boron nitride nanotube reinforced hydroxyapatite composite: Mechanical and tribological performance and in-vitro biocompatibility to osteoblasts. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 4:44-56.
  Full Text via DOI: 10.1016/j.jmbbm.2010.09.005 Web of Science: 000286126400006
- 2011
  
  QBIC, an interdisciplinary and quantitative biological sciences curriculum: Concept to implementation
- 2011
  
  Wear behavior and in vitro cytotoxicity of wear debris generated from hydroxyapatite-carbon nanotube composite coating. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 96A:1-12.
  Full Text via DOI: 10.1002/jbm.a.32952 Web of Science: 000285041400001
- 2010
  
  Structural and functional characterization of the mouse tescalcin promoter. GENE. 464:50-62.
  Full Text via DOI: 10.1016/j.gene.2010.06.002 Web of Science: 000281096300006
- 2010
  
  Boron nitride nanotube reinforced polylactide-polycaprolactone copolymer composite: Mechanical properties and cytocompatibility with osteoblasts and macrophages in vitro. ACTA BIOMATERIALIA. 6:3524-3533.
  Full Text via DOI: 10.1016/j.actbio.2010.02.044 Web of Science: 000281318400018
- 2010
  
  The untranslated side of hair and skin mammalian pigmentation: Beyond coding sequences. IUBMB LIFE. 62:spcone-spcone.
  Full Text via DOI: 10.1002/iub.346
- 2009
  
  Melanocyte pigmentation stiffens murine cardiac tricuspid valve leaflet. JOURNAL OF THE ROYAL SOCIETY INTERFACE. 6:1097-1102.
  Full Text via DOI: 10.1098/rsif.2009.0174 Web of Science: 000270143300012
- 2009
  
  Carbon Nanotube Reinforced Polylactide-Caprolactone Copolymer: Mechanical Strengthening and Interaction with Human Osteoblasts in Vitro. ACS APPLIED MATERIALS & INTERFACES. 1:2470-2476.
  Full Text via DOI: 10.1021/am900423q Web of Science: 000272039700009
- 2008
  
  Timeline and distribution of melanocyte precursors in the mouse heart. PIGMENT CELL & MELANOMA RESEARCH. 21:464-470.
  Full Text via DOI: 10.1111/j.1755-148X.2008.00459.x Web of Science: 000257571300009
- 2008
  
  Endothelin 3 induces skin pigmentation in a keratin-driven inducible mouse model. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 128:131-142.
  Full Text via DOI: 10.1038/sj.jid.5700948 Web of Science: 000251613600018
- 2005
  
  Endothelin-1 and neuregulin-1 convert embryonic cardiomyocytes into cells of the conduction system in the mouse. DEVELOPMENTAL DYNAMICS. 233:20-28.
  Full Text via DOI: 10.1002/dvdy.20284 Web of Science: 000228473800002
- 2004
  
  Early over and Mis-Expression of Endothelin receptor B causes coat color spotting.. PIGMENT CELL & MELANOMA RESEARCH. 17:429-429.
  Full Text via DOI: 10.1111/j.1600-0749.2004.00175_9.x
- 2004
  
  Effects of heregulin-beta1 on neural crest cultures and melanoblast cell lines.. PIGMENT CELL & MELANOMA RESEARCH. 17:450-451.
  Full Text via DOI: 10.1111/j.1600-0749.2004.00175_75.x
- 2003
  
  Role of Pax genes in eye evolution:: A cnidarian PaxB gene uniting Pax2 and Pax6 functions. DEVELOPMENTAL CELL. 5:773-785.
  Full Text via DOI: 10.1016/S1534-5807(03)00325-3 Web of Science: 000186544400014
- 2001
  
  J3-crystallin of the jellyfish lens: Similarity to saposins. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 98:12362-12367.
  Full Text via DOI: 10.1073/pnas.231310698 Web of Science: 000171806100016
- 2001
  
  Tescalcin, a novel gene encoding a putative EF-hand Ca2+-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. ENDOCRINOLOGY. 142:455-463.
  Full Text via DOI: 10.1210/en.142.1.455 Web of Science: 000166308700052
- 1999
  
  Hepatocyte growth factor/scatter factor-MET signaling in neural crest-derived melanocyte development
  Full Text via DOI: 10.1111/j.1600-0749.1999.tb00503.x
- 1998
  
  Sox10 mutation disrupts neural crest development in Dom hirschsprung mouse model
  Full Text via DOI: 10.1038/ng0198-60
- 1998
  
  Endothelin signalling in the development of neural crest-derived melanocytes. BIOCHEMISTRY AND CELL BIOLOGY. 76:1093-1099.
  Full Text via DOI: 10.1139/o99-006
- 1998
  
  Mediolateral patterning of somites: Multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression
  Full Text via DOI: 10.1016/S0925-4773(97)00168-8
- 1997
  
  Squid Pax-6 and eye development. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 94:2421-2426.
  Full Text via DOI: 10.1073/pnas.94.6.2421
- 1997
  
  Eyes absent: A gene family found in several metazoan phyla. MAMMALIAN GENOME. 8:479-485.
  Full Text via DOI: 10.1007/s003359900480
- 1996
  
  Pax-6 and eye development in invertebrates. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 37.
- 1996
  
  Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions
  Full Text via DOI: 10.1016/0925-4773(95)00464-5
- 1993
  
  DEVELOPMENTAL ORIGIN OF SEGMENTAL IDENTITY IN THE LEECH MESODERM. DEVELOPMENT. 117:177-189.
  Web of Science: A1993KP05500014
Book Chapter
- 2013
  
  MC1R, EDNRB and kit signaling in pigmentation regulation related disorders. 57-88.
- 2013
  
  Piebald Trait. 328-330.
  Full Text via DOI: 10.1016/B978-0-12-374984-0.01163-3
- 2003
  
  Molecular biology techniques and applications. 13-1-13-22.
  Full Text via DOI: 10.1201/9780203491492-21
Conference
- 2021
  
  Characterization of a mouse model of leptomeningeal melanocytic disease.. CANCER RESEARCH.
  Web of Science: 000680263506032
- 2017
  
  Abstract 848: Netropsin blocks EMT of murine BRAF mutated melanoma cells. CANCER RESEARCH. 848-848.
  Full Text via DOI: 10.1158/1538-7445.am2017-848
- 2014
  
  Ultraviolet radiation induces carcinogenesis in a novel transgenic mouse model of melanoma. CANCER RESEARCH.
  Full Text via DOI: 10.1158/1538-7445.AM2014-5352 Web of Science: 000349910204271
- 2013
  
  UV radiation interacts with Endothelin 3 and loss of nucleotide excision repair pathway to promote melanomagenesis.. CANCER RESEARCH.
  Full Text via DOI: 10.1158/1538-7445.AM2013-1276 Web of Science: 000331212902260
- 2011
  
  Edn3 promotes metastasis and alters tumor heterogeneity in a mouse model of melanoma. PIGMENT CELL & MELANOMA RESEARCH. 803-804.
  Web of Science: 000294019200171
- 2011
  
  Ets1 interacts with Sox10 during murine melanocyte development. PIGMENT CELL & MELANOMA RESEARCH. 778-778.
  Web of Science: 000294019200087
- 2011
  
  Melanocytes and melanoma cells present different mechanical properties that can be modulated by Endothelin 3. PIGMENT CELL & MELANOMA RESEARCH. 805-805.
  Web of Science: 000294019200175
- 2011
  
  The other ones: non-cutaneous melanocytes. PIGMENT CELL & MELANOMA RESEARCH. 766-766.
  Web of Science: 000294019200050
- 2008
  
  Committed melanocyte precursors reach the heart and persist in the atrioventricular valves in areas of Versican B and elastin expression. PIGMENT CELL & MELANOMA RESEARCH. 309-310.
  Web of Science: 000255061700246
- 2008
  
  Neuregulin/ErbB3 signaling affects early melanocyte development. PIGMENT CELL & MELANOMA RESEARCH. 310-310.
  Web of Science: 000255061700247
Editorial Material
- 2015
  
  Let's make it happen: For gender equality in science!. PIGMENT CELL & MELANOMA RESEARCH. 641-642.
  Full Text via DOI: 10.1111/pcmr.12421
- 2015
  
  What shall we do this year?. PIGMENT CELL & MELANOMA RESEARCH. 1-1.
  Full Text via DOI: 10.1111/pcmr.12342
- 2014
  
  Unmet needs in melanoma research. PIGMENT CELL & MELANOMA RESEARCH. 1003.
  Full Text via DOI: 10.1111/pcmr.12321
Letter
- 2014
  
  Novel UV-induced melanoma mouse model dependent on Endothelin3 signaling. PIGMENT CELL & MELANOMA RESEARCH. 839-842.
  Full Text via DOI: 10.1111/pcmr.12281 Web of Science: 000341778700024
Other Scholarly Work
- 2013
  
  Role of endothelin 3 in melanoma progression and metastasis. CANCER RESEARCH.
  Full Text via DOI: 10.1158/1538-7445.AM2013-2819 Web of Science: 000331212905273
Preprint
- 2019
  
  Suramin potently inhibits binding of the mammalian high mobility group protein AT-hook 2 to DNA
  Full Text via DOI: 10.1101/838656
Review
- 2010
  
  The Untranslated Side of Hair and Skin Mammalian Pigmentation: Beyond Coding Sequences. IUBMB LIFE. 340-346.
  Full Text via DOI: 10.1002/iub.318 Web of Science: 000277602000003
- 2010
  
  Roles of endothelin signaling in melanocyte development and melanoma. PIGMENT CELL & MELANOMA RESEARCH. 160-170.
  Full Text via DOI: 10.1111/j.1755-148X.2010.00678.x Web of Science: 000275466400006

chaired theses and dissertations

Pino, Javier, Transgneic Endothelin 3 Regulates Murine Pigment Production and Coat Color 2017
Li, Xiaoshuang, Identification and Phenotypic Plasticity of Metastatic Cells in a Mouse Model of Melanoma 2017
Chin, Nikeisha L, The Role of Endothelin 3 in Melanoma Progression and Metastasis 2015
Afjei, Feng, A Content Analysis of Sustainability Dimensions in Annual Reports 2015
Benaduce, Ana Paula, UV-Induced Melanoma Mouse Model Dependent on Endothelin 3 Over-Expression 2014
Tavares, Amy Saldana, The Role of the Transcription Factor Ets1 in Melanocyte Development 2014
Lowenstein, Marcia, Interactions between Endothelin Receptor B and Transcription Factors Sox10 and Pax3 in the Melanocyte Lineage 2009
Brito, Flavia Carneiro, Melanocytes in the developing and adult atrioventricular valves of the murine heart 2008
Fernandez, Irina, The role of ErbB3 in melanocyte development 2006
Ayala, Aniveny, Identification of genes downstream of endothelin-3 signaling: characterization of WSB1 and SPC12 2001

advised honors theses

Abujamra, Beatriz Abdo, Elastogenesis in developing murine aortic valve 2019
Lopez, Jesus R., Over-expression of endothelin-3 increases tumor volume in a transgenic murine melanoma model 2019
Durango, Alexander, Mechanism of Endothelin3 Regulation on Murine Coat Color 2018
Torres, Raúl, Timing the Establishment of Metastatic Cell Intravasation in a Mouse Model of Melanoma 2018
Garcia, Ruslan, Effects of Endothelin 3 on the Tumor-Angiogenic Response in a Novel Melanoma Mouse Model 2013
Batista, Deannys, Over-Expression of Endothelin 3 Sensitizes Mice to Uv-Induced Melanoma Metastasis 2012
Diaz, Denisse, Transgenic Expression of Endothelin Receptor-B Rescues the Aganglionosis Phenotype of Piebald Lethal Mice 2008
won, Chulhan K, Cardiac Neural Crest Cells and Their Role in Murine Purkinje Fiber Development 2006
Figueroa, Jessica, Inducible Overexpression of Endothelin-3 in a Transgenic Mouse Leads to Hyperpigmentation That Decreases Over Time 2006
Prado, Jose R. Morillo, Expression of the Myod and T-Box Families of Transcription Factors in the Developing Purkinje Fiber 2005
Piloto, Sarah, Analysis of the Expression Pattern of Wnt Receptor Frizzled 3 2004
Salazar, Armando, Mus Musculus Neural Crest Development: Is Pax3 Regulating the Expression of Endothelin Receptor B? 2002

principal investigator on

The AGEP Florida Alliance Model: Improving Pathways in the Professoriate for Academic Minority Women in STEM awarded by National Science Foundation 2019 - 2024
Phenotypic and functional characterization of neural crest derived aortic valve interstitial cells awarded by Florida Heart Research Foundation Inc 2018 - 2021
The role of metabotropic glutamate receptor 1 signaling in leptomeningeal melanoma awarded by National Cancer Institute 2016 - 2018
The Role of Ets1 in Melanocyte Development awarded by Arthritis & Musculoskeletal & Skin Disea 2012 - 2016
Bridge Funding for Dr. Lidia Kos awarded by FIU Office of Research and Economic Deve 2011 - 2012
Generation of a UV-Dependent Mouse Model of Melanoma. awarded by General Medical Sciences 2008 - 2012

co-principal investigator on

Grant
- LSAMP BD: Florida International University FGLSAMP awarded by National Science Foundation 2022 - 2024
- Transdisciplinary Training in Biomolecular and Biomedical Sciences awarded by General Medical Sciences 2019 - 2024
- LSAMP BD: Florida International University FGLSAMP awarded by National Science Foundation 2018 - 2021

subproject principal investigator on

Women's Explorer Award awarded by Herbert Gruber 2022 - 2025
The AGEP Florida Alliance Model: Improving Pathways in the Professoriate for Academic Minority Women in STEM awarded by National Science Foundation 2019 - 2024
The AGEP Florida Alliance Model: Improving Pathways in the Professoriate for Academic Minority Women in STEM awarded by National Science Foundation 2019 - 2024
Developmental origin of elastin producing cells and mechanism underlying elastogenesis in the murine aortic valve awarded by Florida Heart Research Foundation Inc 2022 - 2024

investigator on

Florida International University MARC U*STAR Program awarded by General Medical Sciences 2019 - 2024

ORCID iD

https://orcid.org/0000-0002-4106-695X (confirmed)

visualizations

Co-author Network

Co-investigator Network

publication subject areas

Citation index-derived subject areas the researcher has published in