Srinivasan Chinnapaiyan mentors students in research activities at HWCOM.
Chinnapaiyan is the member of the Society for Reproductive Biology and Comparative Endocrinology, the Society for Personalized Nano-Medicine, and the American Thoracic Society. He has published several research papers in peer reviewed scientific journals and has presented his work both nationally and internationally.
His current research predominantly focuses on mucociliary dysfunction in HIV, smoked substance abuse, and the pathophysiological mechanisms that lead to mucociliary clearance (MCC) suppression in people living with HIV who also smoke tobacco or abuse illicit drugs. β2-agonists mediated MCC is attenuated in chronic airway diseases (COPD /asthma) and smokers, due to TGF-β mediated suppression of CFTR biogenesis and function. Nevertheless, inhibiting TGF-β signaling can restore CFTR function. Moreover, CRISPR-based gene-specific microRNA antagonism approaches in HIV- associated COPD.