FIU Discovery

Tending to the Facial Surfaces of a Mathematical Biology Head-Scratcher: Why Does the Head of the Sea Turtle Natator depressus Resemble a Convex Zygomorphic Dodecahedron?.  Animals.  15.

A Peculiarly Cerebroid Convex Zygo-Dodecahedron is an Axiomatically Balanced "House of Blues": The Circle of Fifths to the Circle of Willis to Cadherin Cadenzas.  SYMMETRY-BASEL.  4:644-666.

Neuroprotective antioxidant STAZN protects against myocardial ischemia/reperfusion injury.  Biochemical Pharmacology.  75:448-456.

Neuroprotective effect of STAZN, a novel azulenyl nitrone antioxidant, in focal cerebral ischemia in rats: Dose-response and therapeutic window.  BRAIN RESEARCH.  1180:101-110.

Stilbazulenyl nitrone decreases oxidative stress and reduces lung injury after hemorrhagic Shock/Resuscitation and LPS.  ANTIOXIDANTS & REDOX SIGNALING.  9:1971-1977.

Neuroprotective effect of STAZN in focal cerebral ischemia: A therapeutic-window study.  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM.  25:s41-s41.

Stilbazulenyl nitrone, a second-generation azulenyl nitrone antioxidant, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat: Neurobehavior, histopathology, and pharmacokinetics.  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.  313:1090-1100.

A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities.  EXPERIMENTAL NEUROLOGY.  191:86-93.

Kinetic studies on stilbazulenyl-bis-nitrone (STAZN), a nonphenolic chain-breaking antioxidant in solution, micelles, and lipid membranes.  Journal of Organic Chemistry.  69:2929-2936.

Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia.  ANNALS OF NEUROLOGY.  54:330-342.

Stilbazulenyl nitrone, a novel azulenyl nitrone antioxidant: improved neurological deficit and reduced contusion size after traumatic brain injury in rats.  JOURNAL OF NEUROSURGERY.  96:1077-1083.

Stilbazulenyl nitrone (STAZN): A nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants.  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.  124:4678-4684.

Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics..  JOURNAL OF BIOLOGICAL CHEMISTRY.  277:1013-1020.

An optimal redox status for the survival of axotomized ganglion cells in the developing retina.  NEUROSCIENCE.  93:313-320.

Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis.  ANNALS OF NEUROLOGY.  44:763-770.

Azulenyl nitrone spin traps protect against MPTP neurotoxicity.  EXPERIMENTAL NEUROLOGY.  152:163-166.

Redox behaviour of azulenyl nitrones: fully reversible one electron oxidation by cyclic voltammetry at potentials in the range of biological antioxidants.  JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2.  1289-1291.

Mutant Cu,Zn superoxide dismutase in motor neuron disease.  AGE.  21:85-89.

Azulenyl nitrones: Colorimetric detection of oxyradical end products and neuroprotection in the gerbil transient forebrain ischemia/reperfusion model.  FREE RADICAL BIOLOGY AND MEDICINE.  24:738-744.

Redox behaviour of azulenyl nitrones: Fully reversible one electron oxidation by cyclic voltammetry at potentials in the range of biological antioxidants.  JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2.  1289-1291.

Highly sensitive colorimetric detection and facile isolation of diamagnetic free radical adducts of novel chromotropic nitrone spin trapping agents readily derived from guaiazulene.  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.  118:905-906.

Oxocycloalkenyl isoxazolium anhydrobases: Synthesis and reactivity studies.  SYNLETT.  1993:866-868.

A New Synthesis of Substituted Azulenes.  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.  111:389-391.

Application of allenylsilanes in a regiocontrolled [3+2] annulation route to substituted isoxazoles.  Heterocycles.  25:277-281.

C-acylation of tertiary enolates via dithioesters.  Synthetic Communications.  12:829-832.

Synthesis of electron rich pseudoazulenyl dinitrones exhibiting low oxidation potential.  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Photographic evidence for the mechanism and regiochemistry of Markovnikov and anti-Markovnikov additions of hydrogen bromide to alkenes.  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

Design, synthesis and neuroprotective effects of azulenyl nitrone spin traps in animal models of cerebral ischemia.  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

STAZN neuroprotection in focal cerebral ischemia in rats in terms of chronic survival and therapeutic window interval.  Stroke. 471-471.

Neuroprotective effect of STAZN, a novel azulenyl nitrone antioxidant, in focal cerebral ischemia in rats.  Stroke. 299-300.

Mutant CuZn superoxide dismutase in motor neuron disease.  JOURNAL OF INHERITED METABOLIC DISEASE. 587-597.

Azulenyl nitrones: Evidence for enhanced free radical scavenging as a ramification of structure and oxidation potential..  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 643-ORGN.

Highly sensitive colorimetric detection and facile isolation of diamagnetic free radical adducts of novel chromotropic nitrone spin trapping agents readily derived from guaiazulene.  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 426-ORGN.

STABILIZED ISOXAZOLIUM ANHYDROBASES - SYNTHESIS AND REACTIVITY STUDIES.  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 151-ORGN.

Diagnostic and therapeutic applications of azulenyl nitrone spin traps.  CELLULAR AND MOLECULAR LIFE SCIENCES. 626-633.