Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype Article

Wegrzynowicz, Michal, Bichell, Terry Jo, Soares, Barbara D et al. (2015). Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype . 4(1), 17-36. 10.3233/JHD-140116

cited authors

  • Wegrzynowicz, Michal; Bichell, Terry Jo; Soares, Barbara D; Loth, Meredith K; McGlothan, Jennifer L; Alikhan, Fatima S; Hua, Kegang; Coughlin, Jennifer M; Holt, Hunter K; Jetter, Christopher S; Mori, Susumu; Pomper, Martin G; Osmand, Alexander P; Guilarte, Tomas R; Bowman, Aaron B

authors

publication date

  • January 1, 2015

keywords

  • ABNORMALITIES
  • BODY-WEIGHT
  • GENE
  • HUMAN MUTANT HUNTINGTIN
  • Htt aggregates
  • Huntingtin
  • Huntington's disease
  • LENGTH
  • LEPTIN
  • Life Sciences & Biomedicine
  • MICE
  • MICROGLIAL ACTIVATION
  • NEURONAL LOSS
  • Neurosciences
  • Neurosciences & Neurology
  • ONSET
  • Science & Technology
  • Translocator Protein 18 kDa (TSPO)
  • blood markers
  • body weight deficiency
  • brain atrophy
  • inclusion bodies
  • juvenile HD
  • neurodegeneration
  • transgenic mouse

Digital Object Identifier (DOI)

publisher

  • IOS PRESS

start page

  • 17

end page

  • 36

volume

  • 4

issue

  • 1