Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes Article

Cho, Kyoung-in, Yoon, Dosuk, Qiu, Sunny et al. (2017). Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes . DISEASE MODELS & MECHANISMS, 10(5), 559-579. 10.1242/dmm.027730

Open Access

cited authors

  • Cho, Kyoung-in; Yoon, Dosuk; Qiu, Sunny; Danziger, Zachary; Grill, Warren M; Wetsel, William C; Ferreira, Paulo A

sustainable development goals

authors

publication date

  • May 1, 2017

published in

keywords

  • ACUTE NECROTIZING ENCEPHALOPATHY
  • Amyotrophic lateral sclerosis
  • BAC TRANSGENIC MICE
  • BEHAVIORAL DEFICITS
  • BINDING PROTEIN-2 RANBP2
  • CONDUCTION-VELOCITY
  • CYCLOPHILIN DOMAIN
  • Cell Biology
  • Chemokine signaling
  • Life Sciences & Biomedicine
  • Metalloproteinase
  • Motoneuron
  • Mouse gene knock-out
  • NUCLEAR-PORE COMPLEX
  • Nucleocytoplasmic transport
  • Pathology
  • Proteostasis
  • REPEAT EXPANSION
  • Ran-binding protein 2
  • SELECTIVE IMPAIRMENT
  • SUMO E3 LIGASE
  • Science & Technology
  • Transcriptomics

Digital Object Identifier (DOI)

publisher

  • COMPANY OF BIOLOGISTS LTD

start page

  • 559

end page

  • 579

volume

  • 10

issue

  • 5