Aliphatic and Aromatic Oxidations, Epoxidation and S-Oxidation of Prodrugs that Yield Active Drug Metabolites Article

Tekes, K, Kalasz, H, Hasan, MY et al. (2011). Aliphatic and Aromatic Oxidations, Epoxidation and S-Oxidation of Prodrugs that Yield Active Drug Metabolites . CURRENT MEDICINAL CHEMISTRY, 18(32), 4885-4900. 10.2174/092986711797535227

International Collaboration

cited authors

  • Tekes, K; Kalasz, H; Hasan, MY; Adeghate, E; Darvas, F; Ram, N; Adem, A

sustainable development goals

authors

publication date

  • November 1, 2011

webpage

published in

keywords

  • 5-HYDROXYMETHYL METABOLITE
  • Biochemistry & Molecular Biology
  • CAPILLARY-ELECTROPHORESIS
  • CLINICAL PHARMACOKINETICS
  • Chemistry, Medicinal
  • Drugs
  • HUMAN LIVER-MICROSOMES
  • HUMAN-PLASMA
  • IN-VITRO
  • Life Sciences & Biomedicine
  • MAJOR METABOLITES
  • MASS-SPECTROMETRY
  • PERFORMANCE LIQUID-CHROMATOGRAPHY
  • PHASE-I
  • Pharmacology & Pharmacy
  • S-oxidation
  • Science & Technology
  • active metabolites
  • aliphatic oxidation
  • aromatic oxidation
  • cytochrome P450
  • epoxidation
  • hydroxylation
  • lipophilicity
  • logP
  • metabolism
  • total polar surface area

Digital Object Identifier (DOI)

publisher

  • BENTHAM SCIENCE PUBL LTD

start page

  • 4885

end page

  • 4900

volume

  • 18

issue

  • 32