Medicinal Chemistry of Drugs with Active Metabolites (N-, O-, and S-desalkylation and Some Specific Oxidative Alterations) Article

Ram, N, Kalasz, H, Adeghate, E et al. (2012). Medicinal Chemistry of Drugs with Active Metabolites (N-, O-, and S-desalkylation and Some Specific Oxidative Alterations) . CURRENT MEDICINAL CHEMISTRY, 19(33), 5683-5704. 10.2174/092986712803988820

Industry Collaboration International Collaboration

cited authors

  • Ram, N; Kalasz, H; Adeghate, E; Darvas, F; Hashemi, F; Tekes, K

sustainable development goals

authors

publication date

  • November 1, 2012

webpage

published in

keywords

  • Active metabolites
  • Biochemistry & Molecular Biology
  • Chemistry, Medicinal
  • GAS-CHROMATOGRAPHY
  • HPLC METHOD
  • HUMAN PLASMA
  • IN-VITRO
  • LEVO-ALPHA-ACETYLMETHADOL
  • Life Sciences & Biomedicine
  • MAJOR METABOLITE
  • MOUSE PLASMA
  • MS/MS METHOD
  • N-demethylation
  • N-desalkylation
  • N-desethylation
  • O-demethylation
  • O-desethylation
  • PERFORMANCE LIQUID-CHROMATOGRAPHY
  • PHARMACOKINETICS
  • Pharmacology & Pharmacy
  • S-demethylation
  • Science & Technology
  • analysis of active metabolites
  • logP
  • total polar surface area

Digital Object Identifier (DOI)

publisher

  • BENTHAM SCIENCE PUBL LTD

start page

  • 5683

end page

  • 5704

volume

  • 19

issue

  • 33