In situ labelling chemistry of respiratory syncytial viruses by employing the biotinylated host-cell membrane protein for tracking the early stage of virus entry.
Article
Zheng, Lin Ling, Yang, Xiao Xi, Liu, Yue et al. (2014). In situ labelling chemistry of respiratory syncytial viruses by employing the biotinylated host-cell membrane protein for tracking the early stage of virus entry.
. Chemical Communications, 50(99), 15776-15779. 10.1039/c4cc06264g
Zheng, Lin Ling, Yang, Xiao Xi, Liu, Yue et al. (2014). In situ labelling chemistry of respiratory syncytial viruses by employing the biotinylated host-cell membrane protein for tracking the early stage of virus entry.
. Chemical Communications, 50(99), 15776-15779. 10.1039/c4cc06264g
An in situ labelling strategy was proposed to produce quantum dot-labelled respiratory syncytial viruses (RSVs) by incorporating the biotinylated membrane protein of the host cells into mature virions, followed by conjugation with streptavidin modified quantum dots (SA-QDs), which has the advantages such as convenience, efficiency and minor influence on viral infectivity and thus could be successfully applied to track the early stage of virus entry.
