A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. Preprint

Chen, Xue, Yao, Haidong, Kashif, Muhammad et al. (2021). A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. . 10.7554/eLife.63284

cited authors

  • Chen, Xue; Yao, Haidong; Kashif, Muhammad; Revêchon, Gwladys; Eriksson, Maria; Hu, Jianjiang; Wang, Ting; Liu, Yiran; Tüksammel, Elin; Strömblad, Staffan; Ahearn, Ian M; Philips, Mark R; Wiel, Clotilde; Ibrahim, Mohamed X; Bergo, Martin O

authors

publication date

  • February 2, 2021

webpage

keywords

  • Animals
  • Aorta
  • Cell Line
  • Cell Proliferation
  • Cellular Senescence
  • Disease Models, Animal
  • HGPS
  • Humans
  • ICMT
  • Lamin Type A
  • Mice
  • Mice, Knockout
  • Myocytes, Smooth Muscle
  • Progeria
  • Protein Methyltransferases
  • Pyrans
  • cell biology
  • inhibitor
  • methylation
  • mouse
  • progeria
  • senescence

Digital Object Identifier (DOI)