Role of ciliary neurotrophic factor in the proliferation and differentiation of neural stem cells. Article

Ding, Jun, He, Zhili, Ruan, Juan et al. (2013). Role of ciliary neurotrophic factor in the proliferation and differentiation of neural stem cells. . Journal of Alzheimer's Disease, 37(3), 587-592. 10.3233/JAD-130527

cited authors

  • Ding, Jun; He, Zhili; Ruan, Juan; Ma, Zilong; Liu, Ying; Gong, Chengxin; Iqbal, Khalid; Sun, Shenggang; Chen, Honghui

authors

abstract

  • Ciliary neurotrophic factor (CNTF) is a pleiotropic cytokine that has been fully studied for its structure, receptor, and signaling pathways and its multiplex effects on neural system, skeletal muscle, and weight control. Recent research demonstrates that CNTF also plays an important role in neurogenesis and the differentiation of neural stem cells. In this article, we summarize the general characteristics of CNTF and its function on neural stem cells, which could be a valuable therapeutic strategy in treating neurological disorders.

publication date

  • January 1, 2013

webpage

published in

keywords

  • Animals
  • Cell Differentiation
  • Cell Proliferation
  • Ciliary Neurotrophic Factor
  • Humans
  • Neural Stem Cells
  • Neurogenesis

Location

  • United States

Digital Object Identifier (DOI)

start page

  • 587

end page

  • 592

volume

  • 37

issue

  • 3