Cloning, characterization, and expression analysis of mouse enamelysin. Other Scholarly Work

Caterina, J, Shi, J, Sun, X et al. (2000). Cloning, characterization, and expression analysis of mouse enamelysin. . Journal of Dental Research, 79(9), 1697-1703. 10.1177/00220345000790091001

cited authors

  • Caterina, J; Shi, J; Sun, X; Qian, Q; Yamada, S; Liu, Y; Krakora, S; Bartlett, JD; Yamada, Y; Engler, JA; Birkedal-Hansen, H; Simmer, JP

authors

abstract

  • Enamelysin is a recently isolated member of the matrix metalloproteinase (MMP) family of extracellular matrix (ECM)-degrading enzymes. Here we describe the isolation and characterization of the mouse enamelysin cDNA. Expression of mouse enamelysin was detectable only in ameloblasts and odontoblasts of developing teeth. Characterization of mouse enamelysin demonstrated that it is highly conserved in both its sequence content and pattern of expression relative to the porcine, human, and bovine homologues previously described.

publication date

  • September 1, 2000

webpage

published in

keywords

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • Cattle
  • Cloning, Molecular
  • DNA, Complementary
  • Gene Expression Regulation, Enzymologic
  • Humans
  • In Situ Hybridization
  • Matrix Metalloproteinase 20
  • Matrix Metalloproteinases
  • Mice
  • Molar
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Swine

Location

  • United States

Digital Object Identifier (DOI)

start page

  • 1697

end page

  • 1703

volume

  • 79

issue

  • 9