Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer's Disease Preprint

Jin, Mengmeng, Xu, Ranjie, Alam, Mahabub Maraj et al. (2021). Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer's Disease . 10.2139/ssrn.3985173

cited authors

  • Jin, Mengmeng; Xu, Ranjie; Alam, Mahabub Maraj; Ma, Ziyuan; Zhu, Sining; Wang, Le; Martini, Alessandra C; Bernabucci, Matteo; Xie, Ping; Kwan, Kelvin; Pang, Zhiping P; Liu, Ying; Head, Elizabeth; Hart, Ronald P; Jiang, Peng

authors

publication date

  • January 1, 2021

keywords

  • 1.1 Normal biological development and functioning
  • 2.1 Biological and endogenous factors
  • 31 Biological Sciences
  • 3101 Biochemistry and Cell Biology
  • Acquired Cognitive Impairment
  • Aging
  • Alzheimer's Disease
  • Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)
  • Brain Disorders
  • Dementia
  • Down Syndrome
  • Genetics
  • Human Genome
  • Intellectual and Developmental Disabilities (IDD)
  • Neurodegenerative
  • Neurological
  • Neurosciences
  • Pediatric Research Initiative
  • Stem Cell Research
  • Stem Cell Research - Induced Pluripotent Stem Cell
  • Stem Cell Research - Induced Pluripotent Stem Cell - Human
  • Stem Cell Research - Nonembryonic - Human

Digital Object Identifier (DOI)