The Roles of γδ T Cells in Hematopoietic Stem Cell Transplantation.
Other Scholarly Work
Ye, Wanyi, Kong, Xueting, Zhang, Wenbin et al. (2020). The Roles of γδ T Cells in Hematopoietic Stem Cell Transplantation.
. CELL TRANSPLANTATION, 29 963689720966980. 10.1177/0963689720966980
Ye, Wanyi, Kong, Xueting, Zhang, Wenbin et al. (2020). The Roles of γδ T Cells in Hematopoietic Stem Cell Transplantation.
. CELL TRANSPLANTATION, 29 963689720966980. 10.1177/0963689720966980
The αβ T-cell-depleted hematopoietic stem cell transplantation (HSCT) leads to lower relapse and better outcome, and may correlate strongly with expansion of donor-derived γδ T cells. γδ T cells play an important role in immune reconstitution and can exert a graft-versus-leukemia effect after HSCT. This review showed the recent literature on immune functions of γδ T cells after HSCT. The discrepancies between studies of γδ T cells in graft-versus-host disease may cause by its heterogeneous and various distinct subsets. And reconstitution of γδ T cells may play a potential immunoregulatory role in the infections after HSCT.
