Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: The Heart Outcomes Prevention Evaluation (HOPE)-2 trial Article

Lonn, E, Held, C, Arnold, JMO et al. (2006). Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: The Heart Outcomes Prevention Evaluation (HOPE)-2 trial . Canadian Journal of Cardiology, 22(1), 47-53. 10.1016/S0828-282X(06)70238-0

Open Access

cited authors

  • Lonn, E; Held, C; Arnold, JMO; Probstfield, J; McQueen, M; Micks, M; Pogue, J; Sheridan, P; Bosch, J; Genest, J; Yusuf, S; Lonn, E; Yusuf, S; Genest, J; Arnold, JMO; Avezum, A; Bosch, J; Choy, J; Dagenais, G; Davies, R; Fisher, M; Fodor, G; Hamalainen, T; Heyndrickx, G; Hoeschen, R; Klein, W; Kuritzky, R; Mann, J; McQueen, M; Micks, M; Mitchell, B; Ostergren, J; Piegas, L; Pogue, J; Probstfield, J; Sleight, P; Spinas, G; Sussex, B; Teo, K; Title, L; Tsuyuki, R; Arnold, JMO; Avezum, A; Arnold, A; Auger, P; Bata, I; Bernstein, V; Bourassa, M; Dagenais, G; Fodor, G; Hoeschen, R; Meldrum, D; Pilon, C; Ross, C; Starra, R; Sussex, B; Teo, K; Mann, J; Roccaforte, R; Held, C; Fisher, M; Grover, J; Mathew, J; Probstfield, J; Davies, R; Lonn, E; McQueen, M; Pogue, J; Yusuf, S; Sackett, D; Taylor, W; Collins, R; Pitt, B; Furberg, C; Davis, E; Hennekens, C; Pogue, J; Sheridan, P; Avezum, A; Bosch, J; Cracknell, B; Fuentes, M; Lonn, E; MacKay, C; McQueen, M; Micks, M; Pogue, J; Richardson, L; Riley, J; Sardo, L; Sheridan, P; Stranaghan, A; Villamarin, M; West, W; Miyakoshi, SY; Yusuf, S; Grisold, M; Klein, W; Heyndrickx, G; Alexander, E; Amodeo, C; Araujo, D; Armaganijan, D; Barbatto, H; Bertolami, M; Bodanese, LC; Borelli, F; Brasil, C; Carvalho, A; Chaves, A; Esteves, J; Fichino, M; Garbelini, B; Ghorayeb, N; Greque, G; Carvalhaes, SGM; Malheiros, F; Mozetic, V; de Villalon, MN; Nero, F; Ogawa, C; Passarelli, O; Jaeger, C; Silva, AS; Smith, P; Sousa, AG; Tanajura, LF; Tavares, J; Zatz, H; Abraham, G; Aris-Jilwan, N; Arnold, M; Ashton, T; Auger, P; Baird, M; Baitz, T; Bata, I; Belanger, A; Bernstein, V; Bessoudo, R; Bishop, W; Bogaty, P; Boulianne, M; Brossoit, R; Cameron, W; Campeau, J; Carrier, S; Chan, N; Chan, Y; Chiasson, JL; Choy, J; Cox, J; Crowther, M; Cujec, B; D'Amours, G; Davies, RA; Davies, RF; Dawson, KG; Delage, F; DeRose, G; DeYoung, P; Dion, D; Dong, R; Douketis, J; Drobac, M; Dufton, J; Dupuis, R; Edwards, A; Finkelstein, L; Forbes, T; Fowlis, R; Frohlich, J; Fulop, J; Geddis, R; Gervais, P; Ghosh, S; Giannoccaro, JP; Giannoccaro, P; Giroux, R; Gladstone, P; Glanz, A; Goode, E; Gossard, D; Gosselin, G; Goulet, G; Greenwood, P; Grondin, F; Habib, N; Halle, J; Harris, K; Heath, J; Heule, M; Higginson, L; Hoeschen, B; Houlden, R; Hramiak, IM; Imrie, J; Irving, A; Jenkins, CO; Joyce, C; Kandalaft, N; Kassam, S; Kenshole, A; Kim, H; Kornder, J; Kostuk, WJ; Kumar, G; Kuritzky, R; Kuruvilla, G; Kwok, K; Lakhani, Z; Lamy, A; Lauzon, C; LeBlanc, M; Lee, H; Lee, M; Lent, B; Lesoway, R; Loisel, R; Lonn, E; Ma, P; Machel, T; MacLellan, K; MacRitchie, D; Majumdar, S; Massel, D; Mathew, T; Mehta, P; Meldrum, D; Miller, A; Miller, F; Misterski, J; Mitchell, LB; Montgomery, A; Muzyka, T; Nawaz, S; O'Keefe, D; Ong, G; Pallie, S; Panju, A; Patel, MA; Pearce, A; Pflugfelder, P; Pilon, C; Plourde, P; Poirier, C; Polasek, P; Pruneau, G; Rabkin, S; Ravalia, M; Rebane, T; Ricci, J; Riel, C; Ruet, M; Saulnier, D; Savard, D; Sayeed, M; Selby, A; Sestier, F; Sheridan, W; Sherman, G; Shirley, M; Simkus, G; Singh, N; Smith, R; Southern, R; Spence, D; Starra, R; Steeves, D; Sternberg, L; St-Hilaire, R; Stone, J; Sullivan, H; Sullivan, H; Sullivan, M; Sussex, B; Swan, J; Talibi, T; Tan, P; Tanser, P; Taylor, D; Teo, K; Thomasse, G; Title, L; Tymchak, W; Vakani, T; Vederah, S; Vexler, R; Wagner, K; Walker, M; Weeks, A; Wetmore, S; Wisenberg, G; Wolfe, M; Woo, K; Zinman, B; Juhl, H; Hamalainen, T; Cilaci, S; Friederichs, B; Gordalla, A; Hampel, R; Knauerhase, A; Mann, J; Maus, J; Mayinger, B; Miedlich, S; Miehle, K; Muehldorfer, S; Nast, HP; Paschke, R; Prehn, B; Riel, R; Tirneci, V; van Doorn, LG; Kotrec, M; Krpciar, V; Lietava, J; Albert, X; Masiá, R; Karoni, A; Polo, IG; Suárez, C; Bennermo, M; Bjorkman, H; Ekholm, L; Ericsson, UB; Held, C; Jonasson, T; Katzman, P; Ljungdahl, L; Rosenqvist, U; Svensson, KA; Weber, P; Gerber, P; Moccetti, T; Safwan, E; Spinas, G; Abrams, J; Advani, S; Basli, A; Berger, S; Cohen, G; Danisa, K; Davidson, M; Dimova, A; Forchetti, C; Gage, L; Geohas, J; Gorham, J; Graham, S; Gupta, S; Hart, V; Hoogwerf, B; Horwitz, L; Kohn, R; Lader, E; Lorch, G; Mack, R; Nemanich, J; Parikh, D; Pierpont, G; Primm, RK; Probstfield, J; Rashkow, A; Reiter, P; Rough, R; Schwartz, K; Sridharan, V; Suryaprasad, A; Susmano, A; Utley, R; Wickemeyer, W; Zolty, R

sustainable development goals

authors

publication date

  • January 1, 2006

published in

keywords

  • ARTERY DISEASE
  • CORONARY
  • Cardiac & Cardiovascular Systems
  • Cardiovascular System & Cardiology
  • ENDOTHELIAL FUNCTION
  • FOLATE
  • HOMOCYSTINURIA
  • INJURY
  • Life Sciences & Biomedicine
  • PLASMA HOMOCYSTEINE
  • RESTENOSIS
  • Science & Technology
  • VASCULAR-DISEASE
  • atherosclerosis
  • clinical trials
  • coronary disease
  • homocysteine
  • myocardial infarction
  • stroke

Digital Object Identifier (DOI)

publisher

  • ELSEVIER SCIENCE INC

start page

  • 47

end page

  • 53

volume

  • 22

issue

  • 1