Networked salt-bridges mediate magnesium-dependent conformational dynamics and functional regulation in type IA topoisomerases Article

Seol, Yeonee, Tse-Dinh, Yuk-Ching, Neuman, Keir C. (2026). Networked salt-bridges mediate magnesium-dependent conformational dynamics and functional regulation in type IA topoisomerases . NATURE COMMUNICATIONS, 17(1), 10.1038/s41467-026-72556-9

cited authors

  • Seol, Yeonee; Tse-Dinh, Yuk-Ching; Neuman, Keir C

authors

publication date

  • April 30, 2026

published in

keywords

  • ACTIVE-SITE
  • BINDING
  • CLEAVAGE
  • COLI DNA TOPOISOMERASE
  • ION
  • MECHANISM
  • MG(II)
  • Multidisciplinary Sciences
  • PROTEIN
  • RESIDUES
  • SINGLE-MOLECULE MEASUREMENTS
  • Science & Technology
  • Science & Technology - Other Topics

Digital Object Identifier (DOI)

publisher

  • NATURE PORTFOLIO

volume

  • 17

issue

  • 1