Brain endothelial PTPRO drives LPS-induced metabolic reprogramming and neuroinflammation in sepsis-associated encephalopathy Article

Wu, Fengjiao, Tang, Haitao, Jia, Haoxuan et al. (2026). Brain endothelial PTPRO drives LPS-induced metabolic reprogramming and neuroinflammation in sepsis-associated encephalopathy . Journal of Neuroinflammation, 23(1), 10.1186/s12974-026-03790-7

cited authors

  • Wu, Fengjiao; Tang, Haitao; Jia, Haoxuan; Li, Chang; Song, Yuwei; Hu, Jiwei; Cao, He; Zhang, Benben; Zhang, Xiaoyu; Jiang, Hairui; Pan, Zhengyan; Zhou, Wusheng; Gou, Zongming; Li, Tianzhen; Li, Tianbao; Wang, Hongtao; Wang, Huaxue; Qian, Zhongqing; Wang, Ting

authors

publication date

  • March 29, 2026

published in

keywords

  • Blood-brain barrier
  • Brain endothelial cells
  • DYSFUNCTION
  • Glycolysis
  • HIF-1 alpha
  • HYPOXIA
  • Immunology
  • Life Sciences & Biomedicine
  • Neuroinflammation
  • Neurosciences
  • Neurosciences & Neurology
  • PTPRO
  • Science & Technology
  • Sepsis-associated encephalopathy

Digital Object Identifier (DOI)

publisher

  • BMC

volume

  • 23

issue

  • 1