Possible Link Between Macrocytosis and Hypertriglyceridemia: A Case Report. Article

Purow, Jeremy I, Luzarraga, Joseph, Berkman, Aron. (2025). Possible Link Between Macrocytosis and Hypertriglyceridemia: A Case Report. . CUREUS, 17(9), e92455. 10.7759/cureus.92455

cited authors

  • Purow, Jeremy I; Luzarraga, Joseph; Berkman, Aron

authors

abstract

  • Macrocytosis is relatively common and can be due to various etiologies. More common causes include vitamin B12/folate deficiency, liver disease, alcohol use, hypothyroidism, and myelodysplastic syndrome. A work-up often yields the etiology, but in some patients, it remains elusive. We present a case of a 75-year-old female with persistent and unexplained macrocytosis. A work-up for the common causes was unremarkable. However, she had a markedly elevated triglyceride level. This report implies a possible association between hypertriglyceridemia and macrocytosis. Further study is warranted to explore this relationship and red blood cell uptake of triglycerides.

publication date

  • September 1, 2025

published in

Digital Object Identifier (DOI)

Medium

  • Electronic-eCollection

start page

  • e92455

volume

  • 17

issue

  • 9