Tucatinib, trastuzumab, and capecitabine with stereotactic radiosurgery in patients with brain metastases from HER-2 positive breast cancer (TUTOR): Study protocol for a multicenter phase 1 clinical trial Conference

Sarfraz, Zouina, Ozair, Ahmad, Bardhan, Mainak et al. (2025). Tucatinib, trastuzumab, and capecitabine with stereotactic radiosurgery in patients with brain metastases from HER-2 positive breast cancer (TUTOR): Study protocol for a multicenter phase 1 clinical trial . 26(1), 10.1186/s12885-025-15224-3

Open Access International Collaboration

cited authors

  • Sarfraz, Zouina; Ozair, Ahmad; Bardhan, Mainak; Starosciak, Amy K; Perche, Dilanis C; Hodgson, Lydia C; Odia, Yazmin; Mehta, Minesh P; Kotecha, Rupesh; McDermott, Michael W; Maharaj, Arun; Leon, Ana Cristina Sandoval; Mahtani, Reshma; Ahluwalia, Manmeet S

sustainable development goals

authors

publication date

  • December 4, 2025

keywords

  • CNS METASTASES
  • COMBINATION
  • CRITERIA
  • FUNCTIONAL ASSESSMENT
  • Hormone receptor
  • Life Sciences & Biomedicine
  • Metastatic breast cancer
  • Oncology
  • POPULATION
  • Precision medicine
  • Science & Technology
  • Stereotactic radiotherapy
  • THERAPY
  • TUMORS
  • Targeted therapy
  • Tyrosine kinase inhibitor

Digital Object Identifier (DOI)

publisher

  • BMC

volume

  • 26

issue

  • 1