Clinical and epidemiological evaluation of patients with sporadic colorectal cancer
Article
de Fernandes, GMM, Leme, CVD, Ruiz-Cintra, MT et al. (2014). Clinical and epidemiological evaluation of patients with sporadic colorectal cancer
. 34(4), 216-223. 10.1016/j.jcol.2014.08.001
de Fernandes, GMM, Leme, CVD, Ruiz-Cintra, MT et al. (2014). Clinical and epidemiological evaluation of patients with sporadic colorectal cancer
. 34(4), 216-223. 10.1016/j.jcol.2014.08.001
Background: This study aims to perform a survey on clinical data, sociodemographic andrisk factors from patients with sporadic colorectal cancer (SCRC) treated between 2004 and2008 in the Coloproctology Service of a teaching hospital in the North-western region of SãoPaulo.Methods: We analyzed 749 medical records. Of these, 460 were from colon cancer patientsand 289 from rectal cancer patients. Most of the individuals had white skin and were agedover 62 years. The variables that were analyzed included gender, age, skin color, profes-sional occupation, alcohol drinking and cigarette smoking, family history of cancer, andcomorbidities. The identification of the clinical-sociodemographic profile and risk factors ina population with the SCRC the northwest region of São Paulo was performed to collaboratewith prevention strategies.Results: The occurrence of SCRC did not differ much between genders. The most prevalentprofessional occupations were those related to household chores, agricultural and com-mercial activities. Among the comorbidities, hypertension and cholelithiasis were the mostrepresentative. The most common diagnosis method and treatment for the majority ofpatients were coloscopy and surgery, respectively. On average, the time of the disease pro-gression was eight months. The median number of lymph nodes excised ranged between11 and 14. The most common metastasis was hepatic.Conclusion: The occurrence of colorectal cancer is more frequent in men’s white skin with aged over 62 years. Professional occupation seems to be more important for those exposed to carcinogenic agents. This type of tumor mostly affects the distal regions of the colon and rectum with the occurrence of liver metastasis. The affected individuals usually have low survival due to its high aggressiveness.
