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Implementation of guideline-based lipid reporting and rate of lipid lowering therapy prescription Article

Adhikari, A, Haghamad, A, Huang, X et al. (2025). Implementation of guideline-based lipid reporting and rate of lipid lowering therapy prescription . JOURNAL OF CLINICAL LIPIDOLOGY, 10.1016/j.jacl.2024.12.012

cited authors

  • Adhikari, A; Haghamad, A; Huang, X; Fishbein, J; Vaidean, G; Hirsch, JS; Crawford, JM; Rubin, M; Carrero-Tagle, M; Gianos, E

authors

abstract

  • Lipid goal attainment remains suboptimal due to patient, provider, and system level factors. We aimed to assess whether updated, guideline-based lipid reporting and clinical decision support was associated with different lipid-lowering therapy (LLT) prescription patterns. We conducted a retrospective study in our electronic health record (EHR) comparing prescriptions within 90 days of lab reporting both prior to the reporting change (21,417 patients in 2019-2020) and after (39,866 patients in 2020-2021). We found a significant increase in the initiation of LLT in patients > 40 years of age with LDL-C ≥ 100 mg/dL, with 2377 (11.6%) initiated prior to compared to 6205 (16.3%) after the reporting change (P < .001). Among 4469 adult patients with ASCVD and LDL-C ≥ 70 mg/dL prior to (n = 2040) and after (n = 3277) the reporting change, there was a significantly higher rate of LLT initiation, 444 (25.9%) prior to vs 875 (31.8%) after; P < .001. In conclusion, after implementation of updated guideline-based lipid test reporting, we observed higher initiation rates of LLT for indicated patients. Our study suggests that guideline-based reporting of lipid test results may aid in guideline implementation.

publication date

  • January 1, 2025

published in

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