Ring-Opening of Donor-Acceptor Cyclopropane Diester for the Synthesis of Oxime Esters and 2,3-Dihydroazete Ester Article

Banerjee, P, Yadav, N, Verma, K et al. (2024). Ring-Opening of Donor-Acceptor Cyclopropane Diester for the Synthesis of Oxime Esters and 2,3-Dihydroazete Ester . SYNTHESIS-STUTTGART, 10.1055/a-2335-8566

cited authors

  • Banerjee, P; Yadav, N; Verma, K; Das, A; Kaur, N

authors

abstract

  • A simple and efficient approach for the synthesis of privileged oxime esters by employing donor-Acceptor cyclopropane diesters (DACs) as one of the potential precursors is reported. The strategy involves Lewis acid-catalyzed ring-opening of DACs, resulting in an open-chain intermediate followed by the base-mediated construction of the corresponding oxime esters in a one-pot reaction. Moreover, the process also features the synthesis of diethyl 4-(4-methoxyphenyl)azete-2,2(3H)-dicarboxylate.

publication date

  • January 1, 2024

published in

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