Diagnosis of Pediatrics Epilepsy Based on Graph Analysis of Scalp EEG Applying Mutual Information
Conference
Zarafshan, E, Forouzannezhad, P, Rajaei, H et al. (2022). Diagnosis of Pediatrics Epilepsy Based on Graph Analysis of Scalp EEG Applying Mutual Information
. 1577-1582. 10.1109/CSCI58124.2022.00283
Zarafshan, E, Forouzannezhad, P, Rajaei, H et al. (2022). Diagnosis of Pediatrics Epilepsy Based on Graph Analysis of Scalp EEG Applying Mutual Information
. 1577-1582. 10.1109/CSCI58124.2022.00283
Epilepsy is a brain disorder that causes seizures, affecting nearly half a million children in the US alone. In this study, we aimed to use a nonlinear driven method to characterize scalp EEG recordings of pediatric epilepsy patients (PE: n=7) compared to pediatric control subjects (PC: n=7) in a clinical environment. A time-varying approach was used to construct functional connectivity networks (FCNs) of all subjects. Next, the FCNs are mapped into the form of undirected graphs that are subjected to the extraction of graph theory-based features. An unsupervised clustering technique based on K-mean is used to delineate the PE from the PC group. Our findings show a statistically significant difference in the mean FCNs between PC and PE groups (t(340)=- 15.9899, p < < 0.0001). Performance results showed an accuracy of 92.5% with a sensitivity of 90% and a specificity of 95.3%. This approach can help improve and validate the early diagnosis of PE by applying non-invasive scalp EEG signals.
