Symbolic approaches for finding control strategies in Boolean Networks Conference

Langmead, CJ, Jha, SK. (2008). Symbolic approaches for finding control strategies in Boolean Networks . 6 307-320.

cited authors

  • Langmead, CJ; Jha, SK

abstract

  • We present algorithms for finding control strategies in Boolean Networks (BN). Our approach uses symbolic techniques from the field of model checking.We show that despite recent hardness-results for finding control policies, a model checking-based approach is often capable of scaling to extremely large and complex models. We demonstrate the effectiveness of our approach by applying it to a BN model of embryogenesis in D. melanogaster with 15,360 Boolean variables.

publication date

  • December 1, 2008

International Standard Book Number (ISBN) 13

start page

  • 307

end page

  • 320

volume

  • 6