Two-headed PROTAC: An effective new tool for targeted protein degradation Article

Cyrus, K, Wehenkel, M, Choi, EY et al. (2010). Two-headed PROTAC: An effective new tool for targeted protein degradation . CHEMBIOCHEM, 11(11), 1531-1534. 10.1002/cbic.201000222

cited authors

  • Cyrus, K; Wehenkel, M; Choi, EY; Swanson, H; Kim, KB

authors

abstract

  • Better than one: A novel class of PROTAC that recruits target protein for ubiquitination and subsequent degradation by the proteasome has been successfully synthesized and tested for its activity to degrade a target protein. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

publication date

  • July 26, 2010

published in

Digital Object Identifier (DOI)

start page

  • 1531

end page

  • 1534

volume

  • 11

issue

  • 11