Clinical Profile, Hospital Course and Outcome of Children with COVID-19 Article

Nallasamy, K, Angurana, SK, Jayashree, M et al. (2021). Clinical Profile, Hospital Course and Outcome of Children with COVID-19 . 88(10), 979-984. 10.1007/s12098-020-03572-w

cited authors

  • Nallasamy, K; Angurana, SK; Jayashree, M; Mathew, JL; Bansal, A; Singh, MP; Bora, I; Laxmi, P; Verma, S; Sankhyan, N; Suri, V; Guru, RR; Puri, GD; Kumar, R; Gulla, KM; Saini, AG; Bhagwat, C; Chakraborty, S; Jogu, S; Raithatha, D; Vinod Kumar, M; Sharma, P; Kumar, A; Gupta, C; Kaundal, A; Takia, L; Arul, A; Sidana, V; Mahich, S; Choudhary, C; Chhakchhuak, LO; Thakur, A; Sharma, S; Pratyusha, K; Das, G; Kesavan, S; Barman, P; Thapa, S; Saraf, S; Ramineni, K; Bayye, S; Sharma, R; Jindal, A; Gupta, A; Krishna, V; Kumar, S; Gangadharan, P; Jafra, BS; Bansal, D; Baranwal, A; Saini, L; Sharma, R; Venkatesan, DK; Bansal, D; Nori, H; Gailson, T; Naik, R; Kaur, N; Nagar, N; Ravikumar, N; Tenzin, P; Yadav, J; Vaidya, P; Suri, D; Tiewsoh, K; Goel, M; Ali, D; Vishwa, C; Sugha, V; Kaur, A; Vinod Kumar, M; Awasthi, P; Sharma, G; Behara, S; Rawat, A; Randhawa, MS; Kaur, M; Jindal, A; Agarwal, A; Soni, A; Saini, V; Charaya, S; Bala, A; Koneru, V; Kumar, P; Patra, N; Sharma, I



  • Objectives: To describe the epidemiological and clinical characteristics and outcome of hospitalized children with COVID-19 during the initial phase of the pandemic. Methods: This was a cross-sectional descriptive study conducted at the dedicated COVID-19 hospital of a tertiary care referral center in North India. Consecutive children aged 14 y or younger who tested positive for SARS-CoV-2 by RT-PCR from nasopharyngeal swab between 1 April 2020 and 15 July 2020 were included. Results: Of 31 children with median (IQR) age of 33 (9–96) mo, 9 (29%) were infants. About 74% (n = 23) had history of household contact. Comorbidities were noted in 6 (19%) children. More than half (58%) were asymptomatic. Of 13 symptomatic children, median (IQR) duration of symptoms was 2 (1–5.5) d. Fever (32%) was most common followed by cough (19%), rapid breathing (13%), diarrhea (10%) and vomiting (10%). Severe [n = 4, 13%] and critical [n = 1, 3%] illnesses were noted more commonly in infants with comorbidities. Three (10%) children required PICU admission and invasive ventilation; one died. Median (IQR) length of hospital stay was 15 (11–20) d. Follow up RT-PCR before discharge was performed in 17 children and the median (IQR) duration to RT-PCR negativity was 16 (12–19) d. Conclusions: In the early pandemic, most children with COVID-19 had a household contact and presented with asymptomatic or mild illness. Severe and critical illness were observed in young infants and those with comorbidities.

publication date

  • October 1, 2021

Digital Object Identifier (DOI)

start page

  • 979

end page

  • 984


  • 88


  • 10