Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles Article

Gregson, John M, Freitag, Daniel F, Surendran, Praveen et al. (2017). Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles . 24(5), 492-504. 10.1177/2047487316682186

Open Access Industry Collaboration International Collaboration

cited authors

  • Gregson, John M; Freitag, Daniel F; Surendran, Praveen; Stitziel, Nathan O; Chowdhury, Rajiv; Burgess, Stephen; Kaptoge, Stephen; Gao, Pei; Staley, James R; Willeit, Peter; Nielsen, Sune F; Caslake, Muriel; Trompet, Stella; Polfus, Linda M; Kuulasmaa, Kari; Kontto, Jukka; Perola, Markus; Blankenberg, Stefan; Veronesi, Giovanni; Gianfagna, Francesco; Mannisto, Satu; Kimura, Akinori; Lin, Honghuang; Reilly, Dermot F; Gorski, Mathias; Mijatovic, Vladan; Munroe, Patricia B; Ehret, Georg B; Thompson, Alex; Uria-Nickelsen, Maria; Malarstig, Anders; Dehghan, Abbas; Vogt, Thomas F; Sasaoka, Taishi; Takeuchi, Fumihiko; Kato, Norihiro; Yamada, Yoshiji; Kee, Frank; Mueller-Nurasyid, Martina; Ferrieres, Jean; Arveiler, Dominique; Amouyel, Philippe; Salomaa, Veikko; Boerwinkle, Eric; Thompson, Simon G; Ford, Ian; Jukema, J Wouter; Sattar, Naveed; Packard, Chris J; Majumder, Abdulla al Shafi; Alam, Dewan S; Deloukas, Panos; Schunkert, Heribert; Samani, Nilesh J; Kathiresan, Sekar; Nordestgaard, Borge G; Saleheen, Danish; Howson, Joanna MM; Di Angelantonio, Emanuele; Butterworth, Adam S; Danesh, John

sustainable development goals

authors

publication date

  • March 1, 2017

keywords

  • ACTIVATING-FACTOR ACETYLHYDROLASE
  • CARDIOVASCULAR-DISEASE
  • CORONARY-HEART-DISEASE
  • Cardiac & Cardiovascular Systems
  • Cardiovascular System & Cardiology
  • DARAPLADIB
  • EVENTS
  • GENOME-WIDE ASSOCIATION
  • Human genetics
  • LOCI
  • Life Sciences & Biomedicine
  • PHOSPHOLIPASE A(2) ACTIVITY
  • RISK
  • Science & Technology
  • VARIANTS
  • coronary heart disease
  • darapladib
  • lipoprotein-associated phospholipase A(2)
  • target validation

Digital Object Identifier (DOI)

publisher

  • OXFORD UNIV PRESS

start page

  • 492

end page

  • 504

volume

  • 24

issue

  • 5