Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery Article

Ruiz, Victor H, Encinas-Basurto, David, Sun, Bo et al. (2022). Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery . 14(4), 10.3390/pharmaceutics14040700

Open Access

cited authors

  • Ruiz, Victor H; Encinas-Basurto, David; Sun, Bo; Eedara, Basanth Babu; Dickinson, Sally E; Wondrak, Georg T; Chow, H-H Sherry; Curiel-Lewandrowski, Clara; Mansour, Heidi M

sustainable development goals

authors

publication date

  • April 1, 2022

webpage

keywords

  • ARTIFICIAL MEMBRANE
  • Epiderm (TM) 3D human skin
  • Franz cell
  • HaCaT human skin cell line
  • INFLAMMATION
  • KERATINOCYTES
  • Life Sciences & Biomedicine
  • MOUSE
  • NHEK normal primary human skin cells
  • PENETRATION
  • Pharmacology & Pharmacy
  • Pluronic (R) poloxamer triblock copolymer
  • SIGNAL-TRANSDUCTION INHIBITOR
  • Science & Technology
  • Strat-M synthetic membrane
  • TAK-242
  • TLR4
  • carbomer gel
  • cream
  • diffusion
  • emulsion
  • flux
  • hyaluronic acid (HA) gel
  • hydrogel
  • in vitro cell viability
  • nonmelanoma skin cancers
  • polyethylene glycol (PEG)
  • propylene glycol (PG)
  • resatorvid (TAK-242)
  • retention
  • topical drug delivery

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 14

issue

  • 4