Methylphenidate and Children With Attention Deficit Disorder: Dose Effects on Classroom Academic and Social Behavior Article

Pelham, WE, Bender, ME, Caddell, J et al. (1985). Methylphenidate and Children With Attention Deficit Disorder: Dose Effects on Classroom Academic and Social Behavior . ARCHIVES OF GENERAL PSYCHIATRY, 42(10), 948-952. 10.1001/archpsyc.1985.01790330028003

cited authors

  • Pelham, WE; Bender, ME; Caddell, J; Booth, S; Moorer, SH

authors

abstract

  • The short-term, dose-response effects of methylphenidate hydrochloride were evaluated on academic and social classroom measures in 29 children with attention deficit disorder. In a double-blind, cross-over design with order randomized, children received a placebo for two weeks and three doses of methylphenidate hydrochloride (0.15 mg/kg, 0.3 mg/kg, and 0.6 mg/kg) for one week each. Dependent measures included the output and accuracy of performance in grade-appropriate reading comprehension workbooks and arithmetic problems, spelling word acquisition, and observations of disruptive and on-task behavior. Beneficial drug effects and linear dose-response curves on all dependent measures were found. The results suggest that beneficial methylphenidate effects on classroom behavior may be accompanied by enhanced academic achievement in some hyperactive children. © 1985, American Medical Association. All rights reserved.

publication date

  • January 1, 1985

published in

start page

  • 948

end page

  • 952

volume

  • 42

issue

  • 10