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Benzo[a]pyrene phenols are more potent inducers of CYP1A1, CYP1B1 and COX-2 than benzo[a]pyrene glucuronides in cell lines derived from the human aerodigestive tract.
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Overview
cited authors
Almahmeed, Taghreed; Boyle, Jay O; Cohen, Erik G; Carew, John F; Du, Baoheng; Altorki, Nasser K; Kopelovich, Levy; Fang, Jia-Long; Lazarus, Philip; Subbaramaiah, Kotha; Dannenberg, Andrew J
authors
Lazarus, Philip
publication date
May 1, 2004
published in
Carcinogenesis
Journal
Research
keywords
Aryl Hydrocarbon Hydroxylases
Benzo(a)pyrene
Carcinoma, Squamous Cell
Cell Line
Cyclooxygenase 2
Cytochrome P-450 CYP1A1
Cytochrome P-450 CYP1B1
Glucuronides
Humans
Isoenzymes
Leukoplakia, Oral
Membrane Proteins
Mouth Mucosa
Mouth Neoplasms
Phenols
Prostaglandin-Endoperoxide Synthases
Tongue
Identifiers
Digital Object Identifier (DOI)
https://doi.org/10.1093/carcin/bgh078
Additional Document Info
start page
793
end page
799
volume
25
issue
5