Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers Article

Alabsi, Wafaa, Acosta, Maria F, Al-Obeidi, Fahad A et al. (2021). Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers . 13(8), 10.3390/pharmaceutics13081278

Open Access

cited authors

  • Alabsi, Wafaa; Acosta, Maria F; Al-Obeidi, Fahad A; Hay, Meredith; Polt, Robin; Mansour, Heidi M

sustainable development goals

authors

publication date

  • August 1, 2021

webpage

keywords

  • 3D cell culture
  • ALI
  • DESIGN
  • DIPALMITOYLPHOSPHATIDYLCHOLINE DPPC
  • GLYCOPEPTIDES
  • GLYCOSYLATION
  • Life Sciences & Biomedicine
  • MULTIFUNCTIONAL PARTICLES
  • NANOPARTICLES
  • PULMONARY DELIVERY
  • Pharmacology & Pharmacy
  • RECEPTOR
  • SOLID-PHASE SYNTHESIS
  • SOLUBILITY
  • SPPS
  • Science & Technology
  • TEER
  • air-liquid interface
  • angiotensin
  • brain
  • cell viability
  • glycopeptide
  • in vitro 2D
  • partitioning
  • solid phase peptide synthesis
  • solubility
  • transepithelial electrical resistance

Digital Object Identifier (DOI)

publisher

  • MDPI

volume

  • 13

issue

  • 8