Dominant disease gene gets silenced Note

Xu, Z, Xia, XG. (2005). Dominant disease gene gets silenced . GENE THERAPY, 12(15), 1159-1160. 10.1038/sj.gt.3302537

cited authors

  • Xu, Z; Xia, XG

authors

abstract

  • In summary, these two reports, together with a previous report using similar strategy for treatment of spinal cerebellar ataxia, demonstrate the concept of RNAi therapy in vivo for dominant, gain-of-function type of genetic disorders. Like most of the significant scientific advancements, these findings raise new questions that are critical for further development of clinical RNAi therapy. © 2005 Nature Publishing Group. All rights reserved.

publication date

  • August 1, 2005

published in

Digital Object Identifier (DOI)

start page

  • 1159

end page

  • 1160

volume

  • 12

issue

  • 15