It is commonly accepted that people differ culturally. In the Giger and Davidhizar Transcultural Assessment Model, cultural differences are evident in communication, spatial relationships and needs, social organizations (church, family, kinships, and clubs), time orientation, the ability or desire to control the environment, and biological variations (Giger & Davidhizar, 2008). While many individuals appreciate that there are differences between cultures, what is less well recognized is that people also vary according to biological variations depending on their racial and ethnic group. In the last 15 years, information about biological variations has rapidly expanded and that knowledge is essential in order to understand and provide care to individuals from another culture or another racial and ethnic group. Attention to biological variations related to race and ethnicity, the last component of the Giger and Davidhizar Transcultural Nursing Assessment Model, is a critical phenomenon that needs to be assessed in order to develop and implement a culturally sensitive plan of care in an effort to understand ethnopharmacolgy.