Impact of molecular profiling on clinical trial design for glioblastoma Article

Chakravarti, A, Tyndall, E, Palanichamy, K et al. (2007). Impact of molecular profiling on clinical trial design for glioblastoma . CURRENT ONCOLOGY REPORTS, 9(1), 71-79. 10.1007/BF02951429

cited authors

  • Chakravarti, A; Tyndall, E; Palanichamy, K; Mehta, M; Aldape, K; Loeffler, J

authors

abstract

  • This review highlights the ways in which molecular and genetic profiling of malignant gliomas has led to intelligent clinical trial: design. The review also highlights known resistance mechanisms to conventional therapies in malignant gliomas and potential strategies to overcome these mechanisms with the use of targeted therapy. Copyright © 2007 by Current Medicine Group LLC.

publication date

  • January 1, 2007

published in

Digital Object Identifier (DOI)

start page

  • 71

end page

  • 79

volume

  • 9

issue

  • 1