The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression Article

Brown, Robert V, Wang, Ting, Chappeta, Venkateshwar Reddy et al. (2017). The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression . JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(22), 7456-7475. 10.1021/jacs.6b10028

Open Access Industry Collaboration International Collaboration

cited authors

  • Brown, Robert V; Wang, Ting; Chappeta, Venkateshwar Reddy; Wu, Guanhui; Onel, Buket; Chawla, Reena; Quijada, Hector; Camp, Sara M; Chiang, Eddie T; Lassiter, Quinea R; Lee, Carmen; Phanse, Shivani; Tumidge, Megan A; Zhao, Ping; Garcia, Joe GN; Gokhale, Vijay; Yang, Danzhou; Hurley, Laurence H

sustainable development goals

authors

publication date

  • June 7, 2017

keywords

  • BASE-PAIRS
  • CIRCULAR-DICHROISM
  • Chemistry
  • Chemistry, Multidisciplinary
  • DNA-STRUCTURE
  • FORMING REGION
  • IMATINIB MESYLATE
  • INFLAMMATORY LUNG INJURY
  • K+ SOLUTION
  • PDGF RECEPTORS
  • PROXIMAL PROMOTER
  • Physical Sciences
  • SECONDARY STRUCTURES
  • Science & Technology

Digital Object Identifier (DOI)

publisher

  • AMER CHEMICAL SOC

start page

  • 7456

end page

  • 7475

volume

  • 139

issue

  • 22